For Health Plans

Better metabolic health outcomes at scale

Our AI digital twin™ technology and clinical care team work together to prevent and improve chronic conditions like type 2 diabetes while reducing health plan costs.

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The power of a healthy metabolism

Our outcomes aren’t just clinical — they’re human. With better metabolic health, members wake up with more energy, play with their kids or grandkids a little longer, and enjoy a weekend getaway without packing their meds.

71%

lowered A1C below 6.5% without glucose-lowering medications (except metformin)

-27 lbs

average weight loss

85%

GLP-1 elimination

46%

insulin elimination

*2025 Twin Health group results of the Cleveland Clinic study published in the New England Journal of Medicine Catalyst. Individual results may vary.

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As featured in

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73%

eliminated medications
(including injections)

-2.2

point drop in A1C

Avg among baseline A1C 8.0+

66%

improved hypertension

-14 lbs

lost in 6 months

Avg among BMI 30+

81%

improved cholesterol

78%

improved visceral fat

*2025 Twin Health group results of the Cleveland Clinic study published in the New England Journal of Medicine Catalyst. Individual results may vary.

Meet your
AI digital twin™

The AI digital twin™ shows a member’s metabolism in real-time using data from smart devices to help them make informed choices in their daily life.

Close-up of a person stretching with an orange fitness tracker on their wrist against a blurred orange background.

Walking reduced your glucose levels by 20 points

Keep getting active after meals to reduce spikes and help your body use fuel as energy.

Explore Our Solutions

Validated by clinical research

89% reduced A1C below 7 after one year

Stacked bar chart comparing HbA1c level distribution percentages at Baseline and Year 1 across five ranges: Baseline shows 13% under 6.5, 16% between 6.5 and 7, 28% between 7 and 8, 27% between 8 and 10, and 16% at or above 10; Year 1 shows 53% under 6.5, 36% between 6.5 and 7, and 11% between 7 and 8, with no percentages for higher ranges.

Distribution of HbA1C levels after one year among DT Intervention participants*. Abbreviations: DT - digital twin; HbA1C - hemoglobin A1C

Shamanna P, Erukulapati RS, Shukla A, Shah L, Willis B, Thajudeen M, Kovil R, Baxi R, Wali M, Damodharan S, Joshi S. One-year outcomes of a digital twin intervention for type 2 diabetes: a retrospective real-world study. Scientific Reports. 2024 Oct 26;14(1):25478.

Twin members continue losing weight after stopping GLP-1s

Graph showing percentage weight changed over 52 weeks since GLP-1 discontinuation for Twin Health members and non-members. Twin Health members lost 6.1% weight, while non-members gained 13.1%.

Twin members2

continue to lose ~6% of body weight on average

Patients without Twin

gain back ~13%

1. Based on the semaglutide (Ozempic) clinical trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542252/#dom14725-supitem-0001) N=228
2. Inclusive of Active Commercial Members >=52 weeks  in the Twin T2D Program who stopped GLP-1 >=52 weeks prior to the analysis and had a start BMI >=27

Validated by clinical research

The New England Journal of Medicine (NEJM) Catalyst

The journal published the Cleveland Clinic-led study (NCT05181449) evaluating Twin Health’s AI-powered personalized, precision treatment that redefined type 2 diabetes care.

American Heart Association

Concordance between the Various Cardiovascular Risk Scores: Six Months Results of the Randomised Clinical Trial Evaluating Whole-Body Digital Twin Technology Enabled Precision Nutrition for Remission of Diabetes. Journal of AHA - Circulation, 2022;146:A14842.

American Diabetes Association

Whole Body Digital Twin (WBDT) Enabled Diabetes Reversal—US Real-World Findings. Diabetes. 2024 Jun 14;73(Supplement_1).

JACC Journals

Digital twin in managing hypertension among people with type 2 diabetes: 1-year randomized controlled trial. JACC: Advances. 2024 Sep 1;3(9_Part_2):101172.

Endocrine Society

Impact Of Digital Twin Intervention On Visceral Fat And Glycemic Control In T2dm With Different Levels Of Visceral Fat. J Endocr Soc. 2023 Oct 5;7(Suppl 1):bvad114.874.

Nature

One-year outcomes of a digital twin intervention for type 2 diabetes: a retrospective real-world study. Nature Scientific Reports. 2024 Oct 26;14(1):25478.

Diabetes Technology & Therapeutics

Correlation of Continuous Glucose Monitoring Metrics with HbA1c reduction And Beta Cell Function at one year of Whole-Body Digital Twin Technology for Remission of Diabetes. Diabetes Technology & Therapeutics, Feb 2023.A-1-A-269.

AACE Endocrine Practice™

Digital Twin Technology in Resolving Polycystic Ovary Syndrome and improving Metabolic Health: A comprehensive case study. Endocrine Practice, 2024 May;30(5):(Suppl)S130.

The Lancet

Digital Twin Intervention for Type 2 Diabetes: One-Year Outcomes of a Randomized Trial, LANCET Pre-print SSRN 4499693.

We stand behind our solutions

We’re so confident in the efficacy of our programs that our metabolic health benefits are offered fully at-risk. These programs are based upon the highest quality RCT research, which has been peer-reviewed and published in leading journals.

*Outcomes from a Twin self-insured employer partner

19%

Eligible population activated

within the first year

$8.0k

Annualized savings per member

with at least one high-cost medication

$3.2M

Projected pharmacy savings

annualized across all members with 1 or more high-cost meds*

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Recognized by
the Validation Institute

Endorsed for Clinical Outcomes and Contractual Validity, Twin Health’s transparent, results-based model ensures employers and health plans pay only for outcomes proven to improve health and reduce costs.

Results that speak for themselves

Metabolic healing
A1C improvement
Weight loss
Medication elimination
Cardiovascular risk reduction
Liver & kidney function
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Metabolic healing

77%

Members improved insulin resistance (HOMA2IR)

Among T2D members

78%

% Members improved visceral fat

87%

% Members improved inflammation

Among baseline hsCRP >3

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A1C improvement

83%

% Members 
A1C no longer uncontrolled

Avg among baseline A1C 9.0+

-2.2

A1C reduction

Avg among baseline A1C 8.0+

-1.1

A1C reduction

Avg among baseline A1C

Icon of a bathroom scale with a measuring tape wrapped around it representing weight loss.

Weight loss

-17 lbs

Weight loss achieved

Avg among BMI 40+

-14 lbs

Weight loss achieved

Avg among BMI 30+

75%

% Members lost weight

Outline icon of a capsule pill partially open with three small circular pills inside.

Medication elimination

73%

1+ High cost medications eliminated

49%

GLP-1 Prescriptions eliminated

82%

SGLT2 Prescriptions eliminated

Speedometer icon with a heart symbol below, representing cardiovascular health or risk monitoring.

Cardiovascular risk reduction

66%

% Members improved hypertension

81%

% Members improved cholesterol

Among TG/HDL >=4

77%

% Members improved framingham risk score

Among FRS 20+

Simple black outline icon of a liver and kidney side by side.

Liver & kidney function

69%

% Members improved fatty liver (MAFLD)

86%

% Members improved kidney function (eGFR)

Among Prediabetes and/or Obesity members, eGFR >90

65%

% Members improved kidney function (eGFR)

Among all members eGFR >90

Trusted by leading companies

Drive health outcomes & ROI

Learn how Twin Health partners with employers and health plans to deliver clinically proven, all-fees-at-risk programs that improve member health while reducing costs.‍

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