For Employers

Metabolic health solutions for your people

Our metabolic health benefit combines AI digital twin™ technology with clinical care to address the root cause of type 2 diabetes, obesity, prediabetes, and much more.

Trusted by leading companies

The power of a healthy metabolism

Our outcomes aren’t just clinical — they’re human. With better metabolic health, members wake up with more energy, play with their kids or grandkids a little longer, and enjoy a weekend getaway without packing their meds.

71%

lowered A1C below 6.5% without glucose-lowering medications (except metformin)

-27 lbs

average weight loss

85%

GLP-1 elimination

46%

insulin elimination

*2025 Twin Health group results of the Cleveland Clinic study published in the New England Journal of Medicine Catalyst. Individual results may vary.

Explore Twin

The weight loss GLP-1 model that aligns lasting health with lower costs

We prescribe GLP-1s when it's right with an overall goal of helping members safely stop GLP-1s with greater weight loss and results that last. Our care teams guide optimal use and our Al Digital Twin provides real-time health insights from first to last dose and beyond. Result: employers support their team's health with precision care, their choice of four Rx coverage models, and at lower costs.

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The key to healing chronic conditions

Metabolic issues like inflammation and insulin resistance are behind many chronic health conditions. By working with a member’s unique metabolism, Twin Health’s programs address and improve many of the symptoms of metabolic conditions:

Hypertension

Inflammation

Insomnia

Fatigue

Chronic aches & pains

Immune function

Insulin resistance

Reliance on medications

Visceral fat

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What our clients are saying

The highlight for us has been the flexibility....but more importantly the clinical integrity of your product and services.

Chief Clinical Officer at Leading Global Investment Firm

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Twin has been excellent to work with to deliver cost-effective solutions.

Sr. Benefits Leader at Diversified Holdings Company

Independently validated by Duke-Margolis

Twin has been featured in the Capital Impact Council's Health Value-Evidence Quality framework.

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Twin members continue to lose weight after stopping GLP-1s

Chart comparing weight change weeks after GLP-1 discontinuation between Twin Health members and non-members over time. Twin Health members lose about 6% body weight (-2.5%, -5.2%, -6.2%, -6.1%) while patients without Twin Health regain about 13% weight (3.8%, 6.8%, 12.2%, 13.1%).

1. Based on the semaglutide (Ozempic) clinical trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542252/#dom14725-supitem-0001) N=228

2. Inclusive of Active Commercial Members >=52 weeks  in the Twin T2D Program who stopped GLP-1 >=52 weeks prior to the analysis and had a start BMI >=27

Twin members continue losing weight after stopping GLP-1s

Twin members2

continue to lose ~6% of body weight on average

Patients without Twin

gain back ~13%

1. Based on the semaglutide (Ozempic) clinical trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542252/#dom14725-supitem-0001) N=228
2. Inclusive of Active Commercial Members >=52 weeks  in the Twin T2D Program who stopped GLP-1 >=52 weeks prior to the analysis and had a start BMI >=27

Validated by clinical research

The New England Journal of Medicine (NEJM) Catalyst

The journal published the Cleveland Clinic-led study (NCT05181449) evaluating Twin Health’s AI-powered personalized, precision treatment that redefined type 2 diabetes care.

American Heart Association

Concordance between the Various Cardiovascular Risk Scores: Six Months Results of the Randomised Clinical Trial Evaluating Whole-Body Digital Twin Technology Enabled Precision Nutrition for Remission of Diabetes. Journal of AHA - Circulation, 2022;146:A14842.

American Diabetes Association

Whole Body Digital Twin (WBDT) Enabled Diabetes Reversal—US Real-World Findings. Diabetes. 2024 Jun 14;73(Supplement_1).

JACC Journals

Digital twin in managing hypertension among people with type 2 diabetes: 1-year randomized controlled trial. JACC: Advances. 2024 Sep 1;3(9_Part_2):101172.

Endocrine Society

Impact Of Digital Twin Intervention On Visceral Fat And Glycemic Control In T2dm With Different Levels Of Visceral Fat. J Endocr Soc. 2023 Oct 5;7(Suppl 1):bvad114.874.

Nature

One-year outcomes of a digital twin intervention for type 2 diabetes: a retrospective real-world study. Nature Scientific Reports. 2024 Oct 26;14(1):25478.

Diabetes Technology & Therapeutics

Correlation of Continuous Glucose Monitoring Metrics with HbA1c reduction And Beta Cell Function at one year of Whole-Body Digital Twin Technology for Remission of Diabetes. Diabetes Technology & Therapeutics, Feb 2023.A-1-A-269.

AACE Endocrine Practice™

Digital Twin Technology in Resolving Polycystic Ovary Syndrome and improving Metabolic Health: A comprehensive case study. Endocrine Practice, 2024 May;30(5):(Suppl)S130.

The Lancet

Digital Twin Intervention for Type 2 Diabetes: One-Year Outcomes of a Randomized Trial, LANCET Pre-print SSRN 4499693.

We stand behind our solutions

We’re so confident in the efficacy of our programs that our metabolic health benefits are offered fully at-risk. These programs are based upon the highest quality RCT research, which has been peer-reviewed and published in leading journals.

*Outcomes from a Twin self-insured employer partner

19%

Eligible population activated

within the first year

$8.0k

Annualized savings per member

with at least one high-cost medication

$3.2M

Projected pharmacy savings

annualized across all members with 1 or more high-cost meds*

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As featured in

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Recognized by
the Validation Institute

Endorsed for Clinical Outcomes and Contractual Validity, Twin Health’s transparent, results-based model ensures employers and health plans pay only for outcomes proven to improve health and reduce costs.

Drive health outcomes & ROI

Learn how Twin Health partners with employers and health plans to deliver clinically proven, all-fees-at-risk programs that improve member health while reducing costs.‍

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